Yeast strains exhibiting prolonged persistence during a plurality of fermentation cycles
AssigneeDanstar Ferment AG
InventorsEmily Agnes Stonehouse, John McBride, Justin Van Rooyen, Zach Losordo, Petra Deane
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Abstract
The present disclosure provides yeasts, which can be recombinant yeast host cells, exhibiting prolonged persistence when submitted to a plurality of fermentation cycles. The yeasts exhibit at least one of the following phenotypic trait: a fast settling phenotype, a rugose phenotype, an improved invertase activity, triploidy, increased signaling in a RAS/cAMP/PKA pathway or combinations thereof.
Claims20
A recombinant yeast host cell is capable of modulating the activity or the expression of a first polypeptide and/or a second polypeptide for increasing, when compared to a parental cell, the conversion of a biomass into a fermentation product and/or for reducing the conversion of the biomass into a fermentation by-product, wherein the recombinant yeast host cell has at least one of phenotypic trait providing persistence of the recombinant yeast host cell in a plurality of fermentation cycles wherein the at least one phenotypic trait is:
- a fast settling phenotype;
- a rugose phenotype;
- an improved invertase activity;
- triploidy;
- or
- increased signaling in a RAS/cAMP/PKA pathway.
Dependencies are inferred from the claim text.