Back to results
US 2023/0014738 A1Published application
Novel Compositions that Mimic Adipose Tissue in MRI
AssigneeCaliber MRI, Inc.
InventorsElizabeth Mirowski, Michael Snow
Life of this patent
Estimating the term…
Abstract
Provided herein are adipose mimic compositions for use in MRI. The compositions of the invention mimic the MRI properties of human adipose tissue, including T1 relaxation kinetics, T2 relaxation kinetics, magnetic susceptibility, and chemical shift artifact. The compositions of the invention are readily manufactured from inexpensive materials. The compositions of the invention may be used in MRI system calibration or for implementing image correction techniques such as fat suppression.
Claims11
A method of calibrating an MRI system, comprising the steps of
- by the system, measuring the value of a selected MRI property of an adipose mimic composition;
- wherein the adipose mimic composition comprises a mixture of:
- linoleic acid of at least 90% purity and
- oleic acid of at least 90% purity;
- wherein the mixture comprises between 5% and 20% linoleic acid;
- comparing the acquired value of the selected MRI property of the mimic composition against the expected, known value of such MRI property to determine the degree of variance, if any, between the measured and expected value;
- and
- adjusting the MRI system or scan parameters thereof to correct for any observed divergence between the measured value and the expected value of the selected MRI property.
5 more elements
Dependencies are inferred from the claim text.