Composition for treating or preventing an allergy or allergic reaction
AssigneeAposcience AG
InventorsHendrik Jan Ankersmit, Michael Mildner
Life of this patent
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Abstract
The present invention relates to a composition comprising a supernatant of a peripheral blood mononuclear cell (PBMC) cell culture for use in the treatment or prevention of an allergy or an allergic reaction caused by the administration of at least one food and/or inhalation allergen or by the systemic administration of at least one drug to a human or mammal body.
Claims20
A method for treatment or prevention of an allergy or an allergic reaction caused by the administration of at least one food and/or inhalation allergen or by the systemic administration of at least one drug to a human or mammal, comprising:
- administering to the human or mammal a composition comprising a supernatant of a peripheral blood mononuclear cell (PBMC) cell culture, wherein the PBMCs are subjected to ionizing radiation before or during cultivation.
(canceled)
A method for determining the suitability of a composition comprising a supernatant of a peripheral blood mononuclear cell (PBMC) cell culture, wherein the PBMCs are subjected to ionizing radiation before or during cultivation, to be used in the treatment or prevention of an allergy or allergic reactions caused by the administration of at least one food and/or inhalation allergen or by the systemic administration of at least one drug to a human or mammal body, the method comprising the steps of:
- a) contacting at least two skin regions on a mammal with an allergen,
- b) administering said composition to at least one of said skin regions, wherein at least one of said skin regions is not treated with said composition,
- c) comparing the skin regions contacted with the allergen with the skin regions contacted with the allergen and said composition,
- d) identifying a difference between said regions and
- e) determining whether the composition is suited to treat or prevent said disorder or disease.
Dependencies are inferred from the claim text.