Device, system and method for mixing

A mixing system for forming a fibrin foam having a bubble diameter, comprising:

• a first component, a second component, and a system for mixing;
• the system for mixing comprising:
• at least one mixer having two opposing sides and comprising a three-dimensional lattice defining a plurality of tortuous, interconnecting passages therethrough;
• a first container in fluid communication with one side of the mixer and holding the first component therein;
• a second container in fluid communication with the other side of the mixer and holding the second component therein;
• and
• each container being in fluid communication with the other container through the mixer to allow one of the first and second components to flow from one side of the mixer to the other side of the mixer and to allow return flow of both components through the mixer;
• wherein the first component comprises a solution of fibrinogen, the second component comprises a solution of thrombin, and at least one of the first container or second container further comprises a volume of air;
• and
• wherein the fibrin foam is prepared by at least causing one of the first and second components to flow from one side of the mixer to the other side and into the container holding the other of the first and second components and causing return flow of both components through the mixer to form the fibrin foam having a bubble diameter.