Back to results
US 2022/0404346 A1Published application
Method and device for discriminating between viral and bacterial infections
AssigneeDewact Labs GmbH
InventorDetlef Jakschies
Life of this patent
Estimating the term…
Abstract
The present invention relates to a point-of-care assay for detecting and differentiating between viral and bacterial infections, which effectively assist in the rapid differentiation of viral and bacterial infections. More particularly, the invention pertains to an immunoassay that rapidly distinguishes between viral and/or bacterial infections, wherein the viral marker is the interferon induced Mx-B protein and the bacterial markers are CRP/PCT/BPI.
Claims17
1-15. (canceled)
A method for discriminating between a bacterial infection and a viral infection in a subject, the method comprising the steps of:
- (a) providing a sample from the subject;
- (b) providing a point-of-care assay device comprising:
- (i) a sample application zone;
- (ii) a detection zone with detection reagents comprising a first detection reagent with binding affinity to Mx-B-protein (Mx-B), a second detection reagent with binding affinity to C-reactive Protein (CRP), a third detection reagent with binding affinity to procalcitonin (PCT), and a fourth detection reagent with binding affinity to bactericidal/permeability-increasing protein (BPI);
- and
- (iii) a test window configured to allow observation of the test results;
- (c) applying the sample to the sample application zone of the assay device;
- (d) observing the absence or presence of detectable reagent-marker complexes to determine whether the sample contains Mx-B, CRP, PCT, and/or BPI;
- and
- (e) determining the infection status of the subject.
7 more elements
Dependencies are inferred from the claim text.