Methods For Making Microneedles Using Adjustment Of Component Solubility In Casting Formulations
AssigneeGeorgia Tech Research Corporation
InventorsRichard N. Terry, Mark R. Prausnitz
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AssigneeGeorgia Tech Research Corporation
InventorsRichard N. Terry, Mark R. Prausnitz
Estimating the term…
Methods are provided that involve the intentional and controlled precipitation of a drug or active agent, or a reduction of solubility of a polymer or other film-forming component of a formulation, or a combination of both methods, to improve the processes for making microneedles or other objects by casting into molds and the resulting parts produced by casting. The selective reduction in solubility of formulation components solves many problems associated with the casting of polymer formulations into molds. The methods are preferably adapted for making microneedles of biodegradable polymer and drug composites, and may also be used to produce other solid objects formed by casting into molds of compositions containing polymers and active agents.
A method for making a microneedle, the method comprising:
A method for making a microneedle, the method comprising:
A microneedle array for administering a substance of interest into a patient's biological tissue, the microneedle array comprising:
23-31. (canceled)
(canceled)
Dependencies are inferred from the claim text.