Viral inactivation method, method for producing dried amnion, and dried amnion

A method for producing a dried amnion including simultaneously carrying out drying treatment and viral inactivation of a fresh amnion covering a fetus of an animal including human by irradiating with a microwave.

A method for producing a dried amnion

• which uses a drying apparatus equipped with a treatment tank in which an amnion as the object is placed, pressure reduction means for reducing the pressure in the treatment tank, a microwave irradiation device for heating the amnion placed in the treatment tank under reduced pressure and inactivating a virus and pressure recovery means for recovering the reduced pressure in the treatment tank towards atmospheric pressure and
• which includes alternately repeating a pressure reduction step of reducing the pressure in the treatment tank with the pressure reduction means and a pressure recovery step of recovering the pressure in the treatment tank with the pressure recovery means multiple times and
• simultaneously carrying out drying treatment and viral inactivation by irradiating the amnion placed in the treatment tank with a microwave with the microwave irradiation device.

A dried amnion which is obtained through drying treatment of a fresh amnion covering a fetus of an animal including human without damaging the cell tissues of the fresh amnion and

• which is characterized by being subjected to viral inactivation treatment during the drying treatment,
• being dehydrated and dried so as to be stored in a sterilized dry atmosphere and
• retaining the epithelial cells, the basement membrane and the connective tissues that are similar to those of the fresh amnion when being rehydrated by immersing in water or a buffer.