Ophthalmic drug delivery
AssigneeEyenovia, Inc.
InventorsBernard L. Ballou, Jr, Mark Packer, Russell John Mumper, Tsontcho Ianchulev
Life of this patent
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Abstract
The present invention includes and provides a method of delivering a medicament to an eye of a subject in need thereof a solution, the method comprising: (a) providing droplets containing the medicament with a specified average size and average initial ejecting velocity; and (b) delivering the medicament to the eye, where the droplets deliver a percentage of the ejected mass of the droplets to the eye.
Claims21
1-53. (canceled)
A method of delivering droplets to an eye of a subject in need thereof, the method comprising:
- (a) generating the droplets via a piezoelectric actuated ejection device, wherein:
- (i) the droplets comprise a medicament,
- (ii) the droplets have a total volume of less than 15 μl;
- and
- (ii) the piezoelectric actuated ejection device comprises a housing;
- a reservoir containing a composition disposed within the housing;
- and an ejector mechanism fluidly coupled to the reservoir, the ejector mechanism comprising an ejector plate comprising a plurality of openings formed through its thickness, and a piezoelectric actuator coupled to the ejector plate, the actuator being operable to oscillate the ejector plate at a frequency to generate the droplets from the composition upon actuation;
- (b) delivering the droplets to the eye of the subject.
A method of delivering droplets to an eye of a subject in need thereof, the method comprising:
- (a) generating the droplets via a piezoelectric actuated ejection device, wherein:
- (i) the droplets comprise a medicament,
- (ii) the droplets have an average droplet size from about 15 microns to about 100 microns;
- and
- (ii) the piezoelectric actuated ejection device comprises a housing;
- a reservoir containing a composition disposed within the housing;
- and an ejector mechanism fluidly coupled to the reservoir, the ejector mechanism comprising an ejector plate comprising a plurality of openings formed through its thickness, and a piezoelectric actuator coupled to the ejector plate, the actuator being operable to oscillate the ejector plate at a frequency to generate the droplets from the composition upon actuation;
- (b) delivering the droplets to the eye of the subject.
Dependencies are inferred from the claim text.