A Multi-Layered Membrane And A Method Of Preparing The Same
AssigneeNational University of Singapore
InventorsJie Gao, Tai-Shung Chung, Kwee Hiang Jackson Low, Chester Lee Drum, E Shyong Tai
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Abstract
There is provided a multi-layered membrane for separating components in an aqueous sample. There is also provided a method of preparing said multi-layered membrane, a method of separating blood plasma from a whole blood sample and a diagnostic device for separation of blood plasma from a whole blood sample.
Claims21
1-27. (canceled)
A multi-layered membrane for separating components in an aqueous sample comprising:
- a porous layer for separating or retaining at least one component from said aqueous sample therein;
- and
- an absorbent layer comprising a superabsorbent or absorbent material for removing liquid from said porous layer.
A method of preparing a multi-layered membrane comprising a porous layer and an absorbent layer, the method comprising the steps of:
- (a) providing a dope solution of a porous layer material in a solvent;
- (b) casting the dope solution to form the porous layer via a method selected from the group consisting of electrospinning, non-solvent induced phase separation (NIPS), thermally induced phase separation (TIPS), vapor induced phase separation (VIPS), a combination of NIPS and TIPS (N-TIPS), and combinations thereof;
- and
- (c) incorporating the absorbent layer adjacent to the porous layer via physical interaction or chemical treatment, wherein the absorbent layer comprises a superabsorbent or absorbent material for removing liquid from said porous layer.
A method of separating blood plasma from a whole blood sample, comprising applying said whole blood sample to a multi-layered membrane, wherein said multi-layered membrane comprises a porous layer and an absorbent layer comprising a superabsorbent or absorbent material for removing liquid from said porous layer.
A diagnostic device for separation of blood plasma from a whole blood sample, comprising a multi-layered membrane comprising a porous layer and an absorbent layer comprising a superabsorbent or absorbent material for removing liquid from said porous layer.
Dependencies are inferred from the claim text.