Nucleic acid mass spectrum numerical processing method

A numerical processing method for a nucleic acid mass spectrum, comprising:

• step S1, recalibrating a single mass spectrum, for each detection point of a sample, obtaining a plurality of mass spectra corresponding to different positions of the detection point, wherein each mass spectrum of the plurality of mass spectra is recalibrated by using a group of anchor peaks with an expected mass-to-charge ratio;
• step S2, synthesizing the plurality of mass spectra, wherein on a basis of the step S1, the plurality of mass spectra corresponding to the different positions of the detection point are synthesized into a unitary mass spectrum of the detection point;
• step S3:
• performing wavelet filtering on the unitary mass spectrum of the detection point, on a basis of the step S2, to eliminate high-frequency noise and a baseline through a wavelet-based digital filter;
• and
• step S4:
• extracting a peak feature value, performing peak fitting to obtain a fitted curve of the unitary mass spectrum of the detection point on a basis of the step S3, and obtaining a peak height, a peak width, a peak area, a mass offset, and a signal-noise ratio based on the fitted curve of the unitary mass spectrum of the detection point.