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US 2022/0347273 A1Published application
Wound debridement systems
AssigneeRegenics AS
InventorsAdam Robertson, Henrik Lund
Life of this patent
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Abstract
The present invention provides compositions and methods for wound debridement and healing. The debridement compositions preferably comprise a metalloprotease enzyme such as a choriolytic enzyme.
Claims25
A method of debriding a wound comprising contacting the wound with an effective amount of a metalloprotease.
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19-25. (canceled)
A kit or system for treating a wound comprising:
- a first container comprising a metalloprotease in an amount effective to remove devitalized tissue from a wound;
- and
- a second container comprising a wound healing agent.
27-46. (canceled)
A pharmaceutical or cosmetic composition comprising:
- a recombinant metalloprotease selected from the group consisting of a low choriolytic enzyme (LCE), a high choriolytic enzyme (HCE) and combinations thereof;
- and
- one or more pharmaceutically or cosmetically acceptable excipients and/or diluents,
- wherein the composition is a gel, cream, ointment, lotion, foam, non-aqueous solution, spray, salve, stick, soap, powder, film, emulsion, suspension or dispersion and
- wherein the recombinant metalloprotease exhibits metalloprotease activity in an in vitro assay.
2 more elements
50-54. (canceled)
Dependencies are inferred from the claim text.