Methods of Isoprenoid Synthesis Using a Genetically Engineered Hydrocarbonoclastic Organism in a Biofilm Bioreactor
OwnerAndrew P. Magyar, Elizabeth Onderkoinventors
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Abstract
Described herein are genetically-engineered organisms comprising synthetic operons for the production of isoprenoids, carotenoids, and retinoids, optimized for use in a hydrocarbonoclastic organism, and methods for the synthesis and extraction of isoprenoids in a biofilm bioreactor comprising the genetically-engineered organisms.
Claims37
A genetically-engineered hydrocarbonoclastic organism that comprises one, or more variant gene(s) encoding one, or more enzymatic protein(s) of the mevalonate synthetic pathway.
A variant human retinol dehydrogenase 12 (RDH12) gene encoding the retinol dehydrogenase comprising SEQ ID NO:
- 30.
A variant retinol dehydrogenase 12 (RDH12) comprising SEQ ID NO:30.
Dependencies are inferred from the claim text.