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US 2022/0339333 A1Published application
Arrangement for improving the exchange of gases via semipermeable membranes in an aqueous medium
AssigneeProMedTec Germany GmbH
InventorsJan Stange, Jan Klaiber
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Abstract
Provided are methods and arrangements wherein gases are removed via semipermeable membranes from aqueous, optionally complex biological substance mixtures, by dialysis in an aqueous medium. Special carrier molecules for gases are included in the dialysate that are regenerated in the dialysate circuit so that they can be used for further gas exchange cycles on the membrane.
Claims18
A method for influencing the concentration of gases in a composition,
- wherein the gases comprise oxygen and/or carbon dioxide,
- which comprises:
- guiding the composition one-sidedly along an asymmetric, semipermeable membrane,
- guiding a dialysate on a second side of the membrane, wherein the dialysate is oxygenated in a closed circuit comprising an oxygenator,
- wherein the composition comprises corpuscular gas carriers,
- wherein the dialysate comprises a gas carrier for at least one of the gases,
- wherein the gas is placed as closely as possible to the composition, wherein the membrane comprises a greater amount of open pores on the dialysate side than on the second side,
- wherein the gas carrier does not pass through the membrane, and
- wherein the dialysate is regenerated by input of oxygen (O2) and/or by withdrawal of carbon dioxide (CO2).
6 more elements
An arrangement for influencing the concentration of gases in a composition, wherein the gases comprise oxygen and/or carbon dioxide, wherein the arrangement is:
- connectable to a pool and comprises two circuits, wherein a first circuit supplies the composition one-sidedly along a narrow-pore side of an asymmetric, semipermeable membrane from the pool via hoses and pumps,
- wherein the composition is conducted back into the pool via hoses, and
- a second circuit supplies a dialysate on a second side along an open-pore side of the asymmetric, semipermeable membrane via hoses and pumps,
- wherein the dialysate comprises a gas carrier in the form of proteins, and wherein the membrane comprises a greater number of open pores on the dialysate side than on the second side
- wherein the dialysate is conducted back via hoses into a recirculation circuit over a device for regeneration by loading and/or unloading of gases,
- wherein the dialysate is regenerated in the device for regeneration by input of oxygen (O2) and/or by withdrawal of carbon dioxide (CO2).
3 more elements
Dependencies are inferred from the claim text.