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US 2022/0323639 A1Published application
Phosphocalcic cement composition comprising blood
AssigneesCentre National De La Recherche Scientifique, Universite De Nantes, Oniris, Graftys
InventorsJean-Michel BOULER, Olivier GAUTHIER, Bruno BUJOLI, Pascal JANVIER, Charlotte MELLIER
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Abstract
A bone cement paste containing a powder component comprising α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, and a liquid component comprising blood is disclosed. A method for preparation of the phosphocalcic cement composition is also disclosed.
Claims20
A bone cement paste comprising a powder component and a liquid component comprising blood;
- wherein the powder component comprises, in relation to the total weight of the powder component:
- at least 70% by weight of α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, wherein said average size is the mean equivalent diameter of said particles measured by LASER diffraction analysis;
- and
- at least 5% by weight of calcium-deficient apatite (CDA);
- wherein the liquid component (L)/powder component (P) ratio is between 0.3 and 0.7 mL/g;
- and
- wherein the bone cement paste has a setting time ranging from 10 minutes to 72 hours.
4 more elements
An apatitic calcium phosphate cement obtainable by a process comprising the following steps:
- the preparation of a bone cement paste by mixing a powder component and a liquid component comprising blood, and
- wherein the powder component comprises, in relation to the total weight of the powder component:
- at least 70% by weight of α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, wherein said average size is the mean equivalent diameter of said particles measured by LASER diffraction analysis;
- and
- at least 5% by weight of calcium-deficient apatite (CDA);
- wherein the liquid component (L)/powder component (P) ratio is between 0.3 and 0.7 mL/g;
- and
- wherein the bone cement paste has a setting time ranging from 10 minutes to 72 hours;
- and
- the setting of said bone cement paste;
- wherein the apatitic calcium phosphate cement has a compressive strength between 2 MPa and 15 MPa.
8 more elements
Dependencies are inferred from the claim text.