US 2022/0323525 A1Published application

Fuke qianjin tablet and quality control method therefor

AssigneeQianjin Pharmaceutical Co., Ltd.

InventorsDuanyu JIANG, Peng ZHANG, Yun GONG, Fujun LI, Yingshuai ZHANG, Lu BAI, Wei ZHAO, Kanghua WANG, Xiuwei YANG

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Abstract

The present invention discloses Fuke Qianjin Tablets and a quality control method therefor. The Fuke Qianjin Tablets are made of Radix Et Caulis Flemingiae, Caulis Mahoniae, Herba Andrographis, Zanthoxylum dissitum Hemsl., Caulis Spatholobi, Radix Angelicae Sinensis, Radix Codonopsis, and Radix Rosa Laevigata as raw materials. Each of the Fuke Qianjin Tablets contains not less than 0.008 mg of the genistin, not less than 0.7 mg of the Z-ligustilide, and the total amount of the andrographolide and the dehydroandrographolide is not less than 1.1 mg.

Claims21

Dependent claims

A quality control method for Fuke Qianjin Tablets, wherein the quality control method comprises the following steps:

using Radix Et Caulis Flemingiae, Radix Rosa Laevigata, Herba Andrographis, Radix Angelicae Sinensis, Caulis Mahoniae, Zanthoxylum dissitum Hemsl., Caulis Spatholobi and Radix Codonopsis as raw materials;
S1, selecting the Radix Angelicae Sinensis, the Radix Codonopsis, and the Herba Andrographis, crushing into fine powders of 100 meshes or more, respectively, and reserving for use at a powder yield of at least 93.3%;
S2, selecting the Zanthoxylum dissitum Hemsl., the Radix Rosa Laevigata, the Caulis Spatholobi, the Caulis Mahoniae and the Radix Et Caulis Flemingiae, adding water to extract twice, each extraction time being 2 hours, filtering to obtain a filtrate, and concentrating the filtrate into a cream of 1.08/85° C. CF;
and
S3, mixing the fine powders of the step S1 and the cream of the step S2 to obtain a mixture, controlling a content of genistin, a content of at least one of Z-ligustilide and Z-3-butylidenephthalide, and a total amount of andrographolide and dehydroandrographolide in the mixture to reach a standard content;
and then drying, tabletting and coating to obtain the Fuke Qianjin Tablets.

3 more elements

Fuke Qianjin Tablets, made of Radix Et Caulis Flemingiae, Caulis Mahoniae, Herba Andrographis, Zanthoxylum dissitum Hemsl., Caulis Spatholobi, Radix Angelicae Sinensis, Radix Codonopsis, and Radix Rosa Laevigata as raw materials, wherein each of the Fuke Qianjin Tablets contains components listed as the below (1), or (2), or (3):

(1) each of the Fuke Qianjin Tablets contains not less than 0.008 mg of genistin, not less than 0.7 mg of Z-ligustilide, and a total amount of andrographolide and dehydroandrographolide is not less than 1.1 mg;
(2) each of the Fuke Qianjin Tablets contains not less than 0.008 mg of genistin, not less than 0.015 mg of Z-3-butylidenephthalide, and a total amount of the andrographolide and the dehydroandrographolide is not less than 1.1 mg;
(3) each of the Fuke Qianjin Tablets contains not less than 0.008 mg of genistin, not less than 0.7 mg of Z-ligustilide, not less than 0.015 mg of Z-3-butylidenephthalide, and a total amount of andrographolide and dehydroandrographolide is not less than 1.1 mg.

Dependencies are inferred from the claim text.