Chimeric protein and related genic transfer technology
AssigneesLucio Pastore, Eleonora Leggiero
InventorsLucio Pastore, Eleonora Leggiero
Life of this patent
Estimating the term…
Abstract
A human chimeric protein(1) is described, expressed by a viral vector (2) designed for treating patients affected by genetic disorders, composed of a first cDNA sequence [SEQ. 2] of a N-terminal extracellular portion of a human receptor (4) of low-density lipoproteins (5) (hLDLR), fused with a second cDNA sequence [SEQ. 3] of the human transferrin (7) (hTf).
Claims9
A chimeric protein (1) expressed by a viral vector (2) designed, as function of its amino acid and post-translational variations, for treating patients affected by genetic disorders, characterized in that it is human and it is composed of a first cDNA sequence [SEQ.2] of a portion of a human receptor (4) of low-density lipoproteins (5) (hLDLR), and of a second cDNA sequence [SEQ.3] of the human transferrin (7) (hTf) fused in said cDNA sequence of said portion of said human receptor (4) of low-density lipoproteins (5) (hLDLR).
Dependencies are inferred from the claim text.