Methods and compositions involving tert activating therapies
AssigneeBoard of Regents, The University of Texas System
InventorsRonald A. DEPINHO, Yaoqi Alan WANG, Hong Seok SHIM, James W. HORNER
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Abstract
The disclosure provides for methods and compositions for treating a premature aging disorder or neurodegenerative disorder, particularly neurodegenerative disorders associated with amyloid deposition and neuronal death, such as Alzheimer's disease. Accordingly, aspects of the disclosure relate to a method for treating a premature aging disorder in a subject in need thereof, comprising administering a TERT activating therapy to the subject. Further aspects relate to a method for treating a neurodegenerative disorder in a subject comprising administering a TERT activating therapy to the subject.
Claims31
A method for generating new neurons in a subject in need thereof, comprising administering a TERT activating therapy to the subject.
A method for treating a neurodegenerative disorder in a subject comprising administering a TERT activating therapy to the subject.
A method for reducing amyloid-β peptide in a subject in need thereof, comprising administering a TERT activating therapy to the subject.
A method for treating a premature aging disorder in a subject in need thereof, comprising administering a TERT activating therapy to the subject.
Dependencies are inferred from the claim text.