# US 2022/0284606 A1 · Systems and methods for vascular image co-registration > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2022/0284606 A1 - Document ID: US20220284606A1 - Status: Published application - Kind: A1 - Application number: 17/680,482 - Filed: 2022-02-25 - Published: 2022-09-08 - Earliest claimed: 2021-03-05 - Assignees: Boston Scientific Scimed, Inc. - Applicants: Boston Scientific Scimed, Inc. - Inventors: WENGUANG LI; KEVIN BLOMS; MATTHEW R. HUSTON - Web page: https://patentgrep.com/patent/US20220284606A1 ## CPC - A61B 8/463: {characterised by displaying multiple images or images and diagnostic data on one display} - G06T 7/38: Registration of image sequences - A61B 6/12: Arrangements for detecting or locating foreign bodies - A61B 6/4417: {related to combined acquisition of different diagnostic modalities} - A61B 6/463: {characterised by displaying multiple images or images and diagnostic data on one display} - A61B 6/481: {involving the use of contrast agents} - A61B 6/504: {for diagnosis of blood vessels, e.g. by angiography} - A61B 6/5229: {combining image data of a patient, e.g. combining a functional image with an anatomical image} - A61B 8/12: in body cavities or body tracts, e.g. by using catheters - A61B 8/4416: {related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions} - A61B 8/481: {involving the use of contrast agents, e.g. microbubbles introduced into the bloodstream} - A61B 8/5238: {for combining image data of patient, e.g. merging several images from different acquisition modes into one image} - G06T 7/0014: {using an image reference approach} - A61B 2090/3966: {Radiopaque markers visible in an X-ray image} - G06T 2207/10016: Video; Image sequence - G06T 2207/30101: Blood vessel; Artery; Vein; Vascular - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL ## Abstract This disclosure provides alternative medical imaging systems and methods for vascular imaging co-registration. Methods include obtaining extravascular imaging data of a portion of a blood vessel including an extravascular image showing an intravascular imaging device disposed within the vessel with an imaging element disposed at a starting location for a translation procedure. The extravascular image also includes an extravascular contrast image showing the portion of the blood vessel with contrast showing a visualized anatomical landmark. Intravascular imaging data is obtained during the translation procedure that includes one or more intravascular images showing a detected anatomical landmark. The starting location and the ending location of the imaging element on the extravascular imaging data is marked, and the predicted location of the detected anatomical landmark on the extravascular imaging data is marked. The predicted location of the detected anatomical landmark is then aligned with the visualized anatomical landmark. ## Claims ### Claim 1 A method for vascular imaging co-registration, the method comprising: obtaining extravascular imaging data of a portion of a blood vessel, the extravascular imaging data including: an extravascular image showing an intravascular imaging device disposed within the vessel, with an imaging element of the intravascular imaging device disposed at a starting location for a translation procedure during which the imaging element is translated within the blood vessel from the starting location to an ending location; an extravascular contrast image showing the portion of the blood vessel with contrast and showing a visualized anatomical landmark; obtaining intravascular imaging data from the intravascular imaging device during the translation procedure, the intravascular imaging data including one or more intravascular images showing a detected anatomical landmark; marking the starting location and the ending location of the imaging element on the extravascular imaging data; marking a predicted location of the detected anatomical landmark on the extravascular imaging data; and aligning the predicted location of the detected anatomical landmark with the visualized anatomical landmark. ### Claim 2 (depends on 1) The method of claim 1, wherein the extravascular imaging data includes one or both angiographic image data and fluoroscopic image data. ### Claim 3 (depends on 2) The method of claim 2, wherein the angiographic data is selected from one or more of two-dimensional angiographic image data; three-dimensional angiographic image data; or computer tomography angiographic image data. ### Claim 4 (depends on 1) The method of claim 1, wherein the extravascular imaging data is video including the extravascular image showing the intravascular imaging device and the extravascular contrast image showing the portion of the blood vessel with contrast. ### Claim 5 (depends on 1) The method of claim 1, wherein extravascular imaging data is a series of images including the extravascular image showing the intravascular imaging device and the extravascular contrast image showing the portion of the blood vessel with contrast. ### Claim 6 (depends on 1) The method of claim 1, wherein the intravascular imaging data is selected from one or more of intravascular ultrasound data and optical coherence tomography data. ### Claim 7 (depends on 1) The method of claim 1, wherein marking the starting location and the ending location includes using image pattern recognition software, allowing a user to manually mark the starting location and the ending location, or both. ### Claim 8 (depends on 1) The method of claim 1, further including identifying the visualized anatomical landmark on the extravascular imaging data. ### Claim 9 (depends on 8) The method of claim 8, wherein identifying the visualized anatomical landmark on the extravascular imaging data includes allowing a user to manually mark the visualized anatomical landmark on the extravascular imaging data, using image pattern recognition software, or both. ### Claim 10 (depends on 9) The method of claim 9, wherein identifying the visualized anatomical landmark on the extravascular imaging data includes the image pattern recognition software marking the visualized anatomical landmark on the extravascular imaging data. ### Claim 11 (depends on 1) The method of claim 1, wherein marking the predicted location of the detected anatomical landmark on the extravascular imaging data includes using image pattern recognition software, allowing a user to manually mark the predicted location of the detected anatomical landmark on the extravascular imaging data, or both. ### Claim 12 (depends on 1) The method of claim 1, wherein aligning the predicted location of the detected anatomical landmark with the visualized anatomical landmark is performed automatically using software. ### Claim 13 (depends on 1) The method of claim 1, wherein aligning the predicted location of the detected anatomical landmark with the visualized anatomical landmark includes allowing a user to manually align the predicted location of the detected anatomical landmark with the visualized anatomical landmark. ### Claim 14 (depends on 1) The method of claim 1, wherein the translation procedure is performed using an automatic translation system. ### Claim 15 (depends on 1) The method of claim 1, wherein the translation procedure is a pullback. ### Claim 16 (depends on 1) The method of claim 1, wherein during the translation procedure, the imaging element is translated within the blood vessel from the starting location to the ending location at a known speed; and further including: calculating a path on the extravascular imaging data that the imaging element of the intravascular imaging device will travel during the translation procedure from the starting location to the ending location. ### Claim 17 (depends on 16) The method of claim 16, further including: determining the predicted location of the detected anatomical landmark on the extravascular imaging data using the known speed that the imaging element is translated within the blood vessel from the starting location to the ending location. ### Claim 18 (depends on 16) The method of claim 16, wherein marking the predicted location of the detected anatomical landmark on the extravascular imaging data includes: calculating a path on the extravascular imaging data that the imaging element of the intravascular imaging device will travel during the translation procedure from the starting location to the ending location; and determining the predicted location of the detected anatomical landmark on the extravascular imaging data using the known speed that the imaging element is translated within the blood vessel from the starting location to the ending location. ### Claim 19 (depends on 1) The method of claim 1, further including: estimating accuracy of the imaging co-registration, generating a visual indicator representing the estimated accuracy of the imaging co-registration, and displaying the visual indicator overlaid on the portion of the blood vessel on the extravascular imaging data. ### Claim 20 (depends on 1) The method of claim 1, wherein the extravascular imaging data further includes an intermediate extravascular image obtained during the translation procedure showing the intravascular imaging device disposed within the vessel with the imaging element disposed at an intermediate location during the translation procedure between the starting location the ending location; and the method further includes marking the intermediate location of the imaging element on the extravascular imaging data.