# US 2022/0273201 A1 · Integrated sensor assembly unit

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- Number: US 2022/0273201 A1
- Document ID: US20220273201A1
- Status: Published application
- Kind: A1
- Application number: 17/626,005
- Filed: 2020-06-17
- Published: 2022-09-01
- Earliest claimed: 2019-07-12
- Assignees: Ascilion AB
- Applicants: Ascilion AB
- Inventors: Pelle Rangsten; Markus Renlund
- Web page: https://patentgrep.com/patent/US20220273201A1

## CPC

- A61B 5/14514: {using means for aiding extraction of interstitial fluid, e.g. microneedles or suction}
- A61B 5/1468: using chemical or electrochemical methods, e.g. by polarographic means
- A61B 5/150022: {for capillary blood or interstitial fluid}
- A61B 5/150358: {Strips for collecting blood, e.g. absorbent}
- A61B 5/150396: {Specific tip design, e.g. for improved penetration characteristics}
- A61B 5/150969: {Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing}
- A61B 5/150984: {Microneedles or microblades}
- A61B 5/6826: {Finger}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

Sensor assembly comprising a first substrate, a second substrate and a sensor. The first substrate comprises at least one plurality of capillary bores defining a fluid path. The fluid path is extending through said first substrate from a top side to a fluid channel on a bottom side of said first substrate. The second substrate is arranged in connection with the first substrate and the fluid channel of the first substrate is in fluid communication with a first metallised via and a second metallised via formed in the second substrate. Thereby extending the fluid path through the first metallised via and the second metallised via. The sensor comprise a first electrode and a second electrode. The first electrode and the second electrode are arranged on the second substrate in fluid communication with the fluid channel of the first substrate. The first electrode is in electric contact with the first metallised via and the second electrode is in electric contact with the second metallised via.

## Claims

### Claim 1

A sensor assembly, comprising:
a first substrate comprising at least one capillary bore defining a fluid path extending through said first substrate from a top side to a fluid channel on a bottom side of said first substrate;
a second substrate arranged in connection with the first substrate, the fluid channel of the first substrate is in fluid communication with a first metallized via and a second metallized via formed in the second substrate, thereby extending the fluid path through the first metallized via and the second metallized via;
a sensor comprising a first electrode and a second electrode arranged on the second substrate in fluid communication with the fluid channel of the first substrate; wherein the first electrode is in electric contact with the first metallized via and wherein the second electrode is in electric contact with the second metallized via.

### Claim 2 (depends on 1)

A sensor assembly according to claim 1, wherein the first substrate comprise a plurality of bores.

### Claim 3 (depends on 1)

A sensor assembly according to claim 1, further comprising:
means for applying sub-pressure to the fluid path to draw fluid from the capillary bores towards the second substrate.

### Claim 4 (depends on 1)

A sensor assembly according to claim 1, further comprising:
a plurality of microneedles integrally formed on the first substrate, wherein each microneedle comprising:
an elongated body extending from a distal end thereof with a bevel to a proximal end thereof on the first substrate along a longitudinal axis;
wherein the capillary bores extend through the elongated body in a longitudinal direction thereof and further defining the fluid path;
wherein the proximal end is integrally formed with the first substrate and the fluid path is in fluid communication with the fluid channel of the first substrate.

### Claim 5 (depends on 4)

A sensor assembly according to claim 4, wherein the second substrate is arranged in connection with the first substrate on a side opposite the plurality of microneedles.

### Claim 6 (depends on 1)

A sensor assembly according to claim 1, wherein the first electrode is shaped as a spiral and the second electrode is shaped as a spiral, and wherein the spiral shapes of the first and second electrodes are nested.

### Claim 7 (depends on 1)

A sensor assembly according to claim 1, wherein the sensor is located on a side of the second substrate directed towards the first substrate.

### Claim 8 (depends on 1)

A sensor assembly according to claim 1, wherein the sensor is at least partly located on the side of the second substrate that is directed towards the first substrate.

### Claim 9 (depends on 1)

A sensor assembly according to claim 1, wherein the sensor is at least partly located in the first and second vias.

### Claim 10 (depends on 1)

A sensor assembly according to claim 1, wherein the via further comprise a signal path extending through the second substrate and the sensor is arranged in electrical connection with the signal path.

### Claim 11 (depends on 1)

A sensor assembly according to claim 1, wherein the via is hollow, thereby providing fluid communication between two opposite sides of the second substrate.

### Claim 12 (depends on 1)

A sensor assembly according to claim 1, wherein the sensor is an electro-chemical sensor.

### Claim 13 (depends on 1)

A sensor assembly according to claim 1, wherein the wall surface of the vias are hydrophilic.

### Claim 14 (depends on 1)

A measurement device comprising a sensor assembly according to claim 1, further comprising a sub-pressurization device arranged in connection with the sensor assembly on a side opposite the at least one microneedle and in fluid communication with the via of the second substrate, thereby providing sub-pressure through the via and the fluid channel of the chip.
