# US 2022/0264884 A1 · Synergistic fungicide composition > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2022/0264884 A1 - Document ID: US20220264884A1 - Status: Published application - Kind: A1 - Application number: 17/622,379 - Filed: 2020-06-12 - Published: 2022-08-25 - Earliest claimed: 2019-06-24 - Assignees: Upl Ltd - Applicants: Upl Limited - Inventors: Shiv Kumar Sharma; Rajan Ramakant Shirsat; Pradeep Shamrao Sapkale; Chetan Madhukar Zade; Pramod Vidhate; Tusharkumar Bhagwat Chakhale; Umakant Govind Mahajan; Satish Ekanath Bhoge - Web page: https://patentgrep.com/patent/US20220264884A1 ## CPC - A01N 25/12: Powders or granules (A01N25/26 takes precedence) - A01N 47/14: Di-thio analogues thereof - A01N 25/14: wettable - A01N 43/52: condensed with carbocyclic rings, e.g. benzimidazoles - A01N 43/653: 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles - A01N 55/02: containing metal atoms - A01N 59/16: Heavy metals; Compounds thereof - A01N 59/20: Copper - A01P 3/00: Fungicides - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS - A01P: BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS ## Abstract Disclosed herein an improvement in the fungicidal compositions. The present invention relates to a fungicide composition based on dithiocarbamate and another fungicide compound and a method for protecting plants against fungal diseases using said composition. The invention also relates to the water-dispersible granular formulations comprising a combination of mancozeb and a copper fungicide for controlling fungal infection such as Downy Mildew Powdery mildew and Anthracnose. ## Claims ### Claim 1 A fungicidal composition comprising a dithiocarbamate fungicide and at least one another fungicide, wherein said composition is a solid formulation formulated for direct use. ### Claim 2 (depends on 1) The composition as claimed in claim 1, wherein said dithiocarbamate fungicide is selected from group consisting of amobam, asomate, azithiram, carbamorph, cufraneb, cuprobam, disulfiram, ferbam, metam, nabam, tecoram, thiram, urbacide, ziram, dazomet etem, milneb, zineb, propineb, maneb, mancopper, mancozeb, metiram or polycarbamate, and combinations thereof. ### Claim 3 (depends on 1) The composition as claimed in claim 1, wherein said dithiocarbamate fungicide is mancozeb. ### Claim 4 (depends on 1) The composition as claimed in claim 1, wherein said another fungicide is selected from the group consisting of a triazole, a strobilurin, a succinate dehydrogenase inhibitor, a benzimidazole, a benzimidazole precursor, a benzimidazole carbamate fungicide, copper fungicide, and combinations thereof. ### Claim 5 The composition as claimed in claim; wherein said triazole is selected from group consisting of azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, Ipconazole, metconazole, myclobutanil, penconazole, Propiconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, prothioconazole, and combinations thereof. ### Claim 6 (depends on 4) The composition as claimed in claim 4, wherein said succinate dehydrogenase inhibitor is selected from group consisting of benzovindiflupyr, bixafen, fluxapyroxad, furametpyr, isopyrazam, penflufen, penthiopyrad, 3-difluoromethyl-N-(7-fluoro-1, 1, 3-trimethyl-4-indanyl)-1-methyl-4-pyrazolecarboxamide, sedaxane, and combinations thereof. ### Claim 7 (depends on 4) The composition as claimed in claim 4, wherein said benzimidazole precursor fungicide is selected from the group consisting of furophanate, thiophanate, thiophanate-methyl, and combinations thereof. ### Claim 8 (depends on 1) The composition as claimed in claim 1, wherein said dithiocarbamate fungicide is present in an amount of about 40-60% by weight of the composition, based on the total weight of the composition. ### Claim 9 (depends on 1) The composition as claimed in claim 1, wherein said second fungicide is present in an amount of about 10-30% by weight of the composition, based on the total weight of the composition. ### Claim 10 A solid composition comprising a dithiocarbamate fungicide and a second fungicide, wherein said dithiocarbamate fungicide is in an amount of 40-60% by weight of the composition and second fungicide is an amount of 10-30% by weight of the composition, based on the total weight of the composition, wherein the composition is a solid composition formulated for direct use. ### Claim 11 (depends on 10) The solid composition as claimed in claim 10, comprising mancozeb an amount of 40 to 60% by weight and thiophanate methyl in an amount of 20 to 30% by weight, based on the total weight of the composition, wherein said mancozeb and thiophanate methyl are present in a ratio of 2:1. ### Claim 12 (depends on 10) The solid composition as claimed in claim 10, comprising zineb in an amount of 55 to 60% by weight and tebuconazole present in an amount of 10 to 20% by weight, based on the total weight of the composition, wherein said zineb and tebuconazole are present in a ratio of 4:1. ### Claim 13 (depends on 10) The composition as claimed in claim 10, wherein said dithiocarbamate fungicide is mancozeb in an amount of 50% by weight of the composition, based on the total weight of the composition. ### Claim 14 (depends on 10) The composition as claimed in claim 10, wherein said dithiocarbamate fungicide is zineb in an amount of 57% by weight of the composition, based on the total weight of the composition. ### Claim 15 (depends on 10) The composition as claimed in claim 10, wherein said another fungicide is tebuconazole in an amount of 15% by weight of the composition. ### Claim 16 (depends on 10) The composition as claimed in claim 10, wherein said another fungicide is thiophanate methyl an amount of 25% by weight of the composition, based on the total weight of the composition. ### Claim 17 (depends on 1) The composition as claimed in claim 1, further comprising an agrochemically acceptable carrier, filler, or combinations thereof. ### Claim 18 (depends on 17) The composition as claimed in claim 17, wherein said agrochemically acceptable carrier is selected from at least one dispersing agent, at least one wetting agent, at least one antifoam, at least one surfactant, and combinations thereof. ### Claim 19 (depends on 18) The composition as claimed in claim 18, wherein said wetting agent is selected from the group consisting of a salt of an ester of a substituted phenol, and sulfosuccinate. ### Claim 20 (depends on 18) The composition as claimed in claim 18, wherein said surfactant is selected from salts of polystyrenesulphonic acids; salts of polyvinylsulphonic acids; salts of naphthalenesulphonic acid/formaldehyde condensates; salts of condensates of naphthalenesulphonic acid, phenolsulphonic acid and formaldehyde; salts of lignosulphonic acid; sodium lignosulphonate, polyethylene oxide/polypropylene oxide block copolymers; polyethylene glycol ethers of linear alcohols; reaction products of fatty acids with ethylene oxide and/or propylene oxide; polyvinyl alcohol; polyvinylpyrrolidone; copolymers of polyvinyl alcohol and polyvinylpyrrolidone; copolymers of (meth)acrylic acid and (meth)acrylic esters; and alkyl ethoxylates; an alkylarylethoxylates, and combinations thereof. ### Claim 21 (depends on 20) The composition as claimed in claim 20, wherein said surfactant is selected from one or more of sodium alkyl naphthalene sulfonate, sodium diisopropylnaphthalenesulfonate, sodium salt of naphthalene sulfonate condensate, lignin sulfonate salts, and combination thereof. ### Claim 22 (depends on 17) The composition as claimed in claim 17, wherein said filler is-ae selected from one or more of precipitated silica, china clay, and kaolin. ### Claim 23 (depends on 1) The composition as claimed in claim 1, wherein said solid formulation is selected from a dustable powder (DP), a powder for dry seed treatment (DS), microgranules (MG), wettable granules (WG), granules (GR), or a tablet for direct dispersion (DT). ### Claim 24 (depends on 23) The composition as claimed in claim 23, wherein said solid formulation is granules (GR). ### Claim 25 (depends on 10) A solid composition according to claim 10, comprising mancozeb in an amount of 50% by weight and thiophanate methyl an amount of 25% by weight, based on the total weight of the composition, wherein said composition is a granular formulation meant for direct use. ### Claim 26 (depends on 10) The solid composition according to claim 10, comprising zineb in an amount of 57% by weight and tebuconazole in an amount of 15% by weight, wherein said composition is wherein said composition is a granular formulation meant for direct use. ### Claim 27 (depends on 1) A method of treating crop disease comprising applying to the crop composition of claim 1, wherein said crop disease is disease in rice. ### Claim 28 (depends on 27) The method as claimed in claim 27, wherein said crop diseases is selected from blast, Helminthosporium leaf spot, sheath blight, and bakanae disease. ### Claim 29 (depends on 28) The method as claimed in claim 28, wherein said crop diseases is selected from blast and sheath blight. ### Claim 30 A fungicidal composition comprising a dithiocarbamate fungicide and a benzimidazole fungicide or a benzimidazolylcarbamate fungicide, wherein said composition is a solid formulation formulated for direct use. ### Claim 31 (depends on 30) The composition as claimed in claim 30, wherein said dithiocarbamate fungicide and benzimidazole fungicide or benzimidazolylcarbamate fungicide are present in a ratio of 10.08:1.92. ### Claim 32 (canceled) ### Claim 33 (depends on 30) The composition as claimed in claim 30, wherein said dithiocarbamate fungicide is mancozeb. ### Claim 34 (depends on 30) The composition as claimed in claim 30, wherein said benzimidazole fungicide or benzimidazolylcarbamate fungicide is carbendazim. ### Claim 35 (depends on 30) The composition as claimed in claim 30, wherein carbendazim is in an amount of 1.92% by weight of the composition, based on the total weight of the composition. ### Claim 36 (depends on 30) The composition as claimed in claim 30, wherein mancozeb is an amount of 10.08% by weight of the composition, based on the total weight of the composition. ### Claim 37 (depends on 30) The composition as claimed in claim 30, further comprising an agrochemically acceptable carrier, filler, or a combination thereof. ### Claim 38 (depends on 37) The composition as claimed in claim 37, wherein said agrochemically acceptable carrier is selected from at least one dispersing agent, at least one wetting agent, at least one antifoam, at least one surfactant and combinations thereof. ### Claim 39 (depends on 38) The composition as claimed in claim 38, wherein said wetting agent is selected from the group consisting of a salt of an ester of a substituted phenol, and sulfosuccinate. ### Claim 40 (depends on 37) The composition as claimed in claim 37, wherein said filler re selected from one or more of precipitated silica, china clay, and kaolin. ### Claim 41 (depends on 30) A method of treating crop disease comprising applying to the crop composition of claim 30, wherein said crop disease is disease in rice. ### Claim 42 (depends on 41) The method of claim 41, wherein said crop diseases is selected from blast, Helminthosporium leaf spot, sheath blight, and bakanae disease. ### Claim 43 (depends on 42) The method of claim 42, wherein said crop diseases is selected from blast and sheath blight. ### Claim 44 (depends on 30) The composition as claimed in claim 30, wherein said solid formulation is selected from a dustable powder (DP), powder for dry seed treatment (DS), granules (GR), or a tablet for direct dispersion (DT). ### Claim 45 (depends on 44) The composition as claimed in claim 44, wherein said solid formulation is granules (GR). ### Claim 46 A composition comprising mancozeb and a copper fungicide present in a ratio of about 1:1.5. ### Claim 47 (depends on 4) The composition as claimed in claim 4, wherein mancozeb is from about 25% to about 35% by weight of the composition based on the total weight of the composition. ### Claim 48 (depends on 46) The composition as claimed in claim 46, wherein the copper fungicide is from about 40% to about 50% by weight of the composition, based on the total weight of the composition. ### Claim 49 (depends on 46) The composition as claimed in claim 46, wherein said composition comprises about 30% by weight of mancozeb and 47.15% by weight of the copper fungicide, based on the total weight of the composition. ### Claim 50 (depends on 46) The composition as claimed in claim 46, wherein the copper fungicide is selected from copper oxychloride, copper sulfate, copper hydroxide, tribasic copper sulfate, and combinations thereof. ### Claim 51 (depends on 46) The composition as claimed in claim 46, formulated as granules, a dry flowable formulation, wettable granules, or water dispersible granules. ### Claim 52 (depends on 46) The composition as claimed in claim 46, wherein said composition is a solid formulation formulated for direct use. ### Claim 53 (depends on 46) The composition as claimed in claim 46, wherein the total weight of mancozeb and the copper fungicide together is about 75% by weight of the composition based on the total weight of the composition. ### Claim 54 (depends on 53) The composition as claimed in claim 53, wherein the composition is formulated as water dispersible granules. ### Claim 55 (depends on 46) The composition as claimed in claim 46, further comprising an agrochemically acceptable carrier, filler, or a combination thereof. ### Claim 56 (depends on 55) The composition as claimed in claim 55, wherein said agrochemically acceptable carrier is selected from at least one dispersing agent, at least one wetting agent, at least one antifoam, at least one surfactant, and combinations thereof. ### Claim 57 (depends on 55) The composition as claimed in claim 55, wherein said agrochemically acceptable carrier is selected from alkali aromatic aryl sulphonate, salts of condensates of naphthalenesulphonic acid, alkylarylsulfonatesalkylbenzenesulfonates; alkylnaphthalenesulfonates, and salts thereof. ### Claim 58 (depends on 46) A method of treating crop disease comprising applying to the crop the composition of claim 46, wherein said crop disease is disease in grape. ### Claim 59 (depends on 46) The method of claim 46 wherein said crop diseases is selected from anthracnose, powdery, and downy mildew diseases of grapes. ### Claim 60 (depends on 46) The composition as claimed in claim 46, wherein said composition is a solid formulation selected from a dustable powder (DP), a powder for dry seed treatment (DS), granules (GR), or a tablet for direct dispersion (DT). ### Claim 61 (depends on 60) The composition as claimed in claim 60, wherein said formulation is granules (GR). ### Claim 62 A process for preparation of granular formulation comprising mancozeb and a copper fungicide, said process comprising: a) blending mancozeb with the copper fungicide, optionally with at least one agrochemically acceptable carriers and water, to prepare a slurry; b) homogenizing said slurry by wet milling; and c) spray drying the slurry of step (b) to obtain granules. ### Claim 63 A method for controlling pathogenic fungi at a locus, said method comprising contacting the locus with a composition comprising a mancozeb and a copper fungicide, wherein said mancozeb and copper fungicide are present in a ratio of about 1:1.5. ### Claim 64 (depends on 4) The composition as claimed in claim 4, wherein said strobilurin fungicide is selected from group consisting of azoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, picoxystrobin, pyraoxystrobin, mandestrobin, pyraclostrobin, pyrametostrobin, triclopyricarb, kresoxim-methyl, dimoxystrobin, fenaminostrobin, metominostrobin, trifloxystrobin, famoxadone, fluoxastrobin, fenamidone, pyribencarb, and mixtures thereof.