Back to results
US 2022/0243230 A1Published application
Bioconversion of 4-coumaric acid to resveratrol
AssigneeConagen Inc.
InventorsGrace Park, Ernesto Simon
Life of this patent
Estimating the term…
Abstract
The present invention relates, at least in part, to the production of resveratrol from 4-coumaric acid. The production can be mediated in a transgenic Saccharomyces cell.
Claims28
A microorganism of the genus Saccharomyces, comprising a disrupted gene encoding an enzyme involved in the degradation of phenylpyruvate to phenylacetaldehyde.
A method of producing resveratrol using a recombinant Saccharomyces cell, the method comprising:
- (i) cultivating a recombinant Saccharomyces cell in a medium;
- (ii) adding 4-coumaric acid to the medium to initiate the bioconversion of 4-coumaric acid to resveratrol;
- and
- (iii) extracting resveratrol from at least one of the recombinant cell and medium, wherein the recombinant Saccharomyces cell has been transformed to disrupt a gene encoding an enzyme involved in the degradation of phenylpyruvate to phenylacetaldehyde.
1 more element
Dependencies are inferred from the claim text.