Method To Evaluate Metabolic Activity Of Liver Enzymes
AssigneeOwlstone Medical Limited
InventorsEdoardo Gaude, Max Allsworth, Marc van der Schee
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Abstract
The invention provides a breath test for assessing a metabolic phenotypeand/or assessing a disease state.
Claims26
A method for determining the metabolic activity of a liver enzyme comprising at least one of measuring the concentration of a substrate for a liver enzyme and measuring the concentration of a metabolite of said substrate in exhaled breath of a subject wherein at least one of said substrate and its metabolite is a VOC and wherein the substrate is a non-isotope labelled GRAS compound.
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A system for determining metabolic activity of a liver enzyme comprising at least one of measuring the concentration of a substrate for a liver enzyme and measuring the concentration of a metabolite of said substrate in exhaled breath of a subject wherein at least one of said substrate and its metabolite is a VOC wherein said system comprises a device for capturing a breath sample from a patient and wherein the substrate is a non-isotope labelled GRAS compound.
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Dependencies are inferred from the claim text.