Multiplex synthesis method of compound library and parallel synthesizer of compound library using same
AssigneePostech Research and Business Development Foundation
InventorsDong Pyo KIM, Gwang Noh AHN
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Abstract
The present invention relates to a parallel synthesis method and synthesizer of a compound library, and more specifically provides a parallel synthesis method and synthesizer of a compound library, which uniformly distribute a first reactant and perform independent reactions in separate spaces, and since it is possible to confirm the results for various reaction variables at once, the synthesis time of the compound library can be reduced with a high synthesis yield of the product.
Claims14
A parallel synthesis method of a compound library, comprising:
- a) introducing a first reactant at a controlled flow rate to be distributed into a plurality of accommodation spaces;
- b) introducing a second reactant into each of the plurality of accommodation spaces to mix with the first reactant;
- and
- c) after each independent chemical reaction is performed in the accommodating space, discharging the product of the chemical reaction through a discharge unit on one side of the accommodation space,
- wherein the temperature and time of the chemical reaction in the plurality of accommodation spaces can be independently controlled.
A parallel synthesizer of a compound library, comprising:
- a first inlet unit through which a first reactant is introduced and at least one inlet is formed;
- a flow distributor connected to the first inlet unit and distributing the introduced first reactant in equal amounts, and formed with a damper and a baffle;
- a plurality of ducts connected to the flow distributor and through which the distributed first reactant passes, respectively;
- a second inlet unit located at one side of the duct and formed with an inlet through which a second reactant is introduced;
- a plurality of reactors respectively connected to the duct and in which a product is generated by a chemical reaction of the first reactant and the second reactant transported through the duct;
- and
- a discharge unit formed on one side of the reactor to discharge the product,
- wherein the temperature and time of the chemical reaction can be independently controlled in each of the reactors.
Dependencies are inferred from the claim text.