Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
AssigneesThe Board of Trustees of the Leland Stanford Junior University, The United States Government AS Represented By the Department Affairs Office of the General Counsel
InventorsAnton Wyss-Coray, Thomas A. Rando, Markus Britschgi, Kaspar Rufibach, Saul A. Villeda
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Abstract
Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include modulating CCR3, e.g., by modulating eotaxin-1/CCR3 interaction, in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments.
Claims23
A method of treating an adult mammal for an aging-associated impairment, the method comprising:
- modulating CCR3 in the mammal in a manner sufficient to treat the adult mammal for the aging-associated impairment.
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Dependencies are inferred from the claim text.