Monocyte compositions and methods for the treatment of infectious disease
AssigneesThe General Hospital Corporation, President and Fellows of Harvard College
InventorsCatherine Rhee, David T. Scadden
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Abstract
Described herein are compositions comprising subsets of monocyte having distinct functional properties and methods for using the same to treat infectious disease.
Claims17
A method of treating a microbial infection in a tissue of a subject, the method comprising administering to the subject a composition comprising isolated monocyte cells that express Cd49f, Cd54, and Cd11b, thereby treating the microbial infection in the tissue of the subject.
A composition comprising isolated monocytic cells that express Cd49f, Cd54, and Cd11b, wherein the cells comprise exogenous nucleic acid sequences recombined into their genomic DNA.
Dependencies are inferred from the claim text.