Composition for promoting production of stem cell-derived exosomes and increasing stemness
AssigneeBrexogen Inc.
InventorsSue KIM, Seulki LEE, Jimin KIM
Life of this patent
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Abstract
The present disclosure relates to a composition for promoting the production of stem cell-derived exosomes or increasing the stemness of stem cells. When the composition of the present disclosure is used in culturing stem cells, the stemness of stem cells and the yield of stem cell-derived exosomes are increased, and thus good-quality stem cells and stem cell-derived exosomes can be produced more efficiently, and accordingly, can be advantageously used in related research and development and commercialization.
Claims9
-9. (canceled)
A method for producing stem cell-derived exosomes, the method comprising a step of:
- culturing stem cells in a cell culture medium containing at least one selected from the group consisting of exendin-4, phorbol 12-myristate 13-acetate (PMA), interferon-γ, tetrandrine, hyaluronic acid, substance P, resveratrol, and lanifibranor.
A method for increasing stemness of stem cells, the method comprising a step of:
- culturing stem cells in a cell culture medium containing at least one selected from the group consisting of exendin-4, phorbol 12-myristate 13-acetate (PMA), interferon-γ, tetrandrine, hyaluronic acid, substance P, resveratrol, and lanifibranor.
Dependencies are inferred from the claim text.