Tetrapyrrolic conjugates and uses thereof for imaging
OwnerRavindra K. PANDEY, Mykhaylo DUKH +2inventors
InventorsRavindra K. PANDEY, Mykhaylo DUKH, Aimee MARKO, Munawwar SAJJAD
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Abstract
Compounds for tumor imaging (e g , magnetic resonance (MR) and fluorescence) that may be used in combination with other methods to treat an individual having or suspected of having cancer (e.g., various forms of cancer, such as, for example, solid tumors). Compounds may have the following structure: (I) or a salt, a partial salt, a hydrate, a polymorph, an isomer (e.g., a structural or stereoisomer), or a mixture thereof, where R′ is an aryl group or heteroaryl group having a halogen group (e.g., I or 124I), X is chosen from O, S, or NH, n is 1-6 (e.g., 1, 2, 3, 4, 5, or 6), the dotted carbon is chiral and is R or S.
Claims15
A compound having the following structure:
- or a salt, a partial salt, a hydrate, a polymorph, an isomer, or a mixture thereof, wherein R′ is an aryl or heteroaryl group having a halogen group, X is chosen from O, S, or NH, n is 1-6, and the dotted carbon is chiral and is R or S.
Dependencies are inferred from the claim text.