Glycan mass spectrometry data analyzer and program for analyzing glycan mass spectrometry data

A non-transitory computer readable medium recording a glycan-mass-spectrometry-data analyzing program for analyzing mass spectrum data obtained by a mass spectrometric analysis of a sample containing a sialic-acid-linked glycan subjected to a derivatization treatment specific to a sialic-acid linkage type or a molecule modified with the sialic-acid-linked glycan, wherein the program is configured to make a computer function as:

• a glycan composition setting section configured to allow a setting of a glycan composition of an analysis target;
• a glycan information acquisition section configured to acquire a plurality of kinds of glycans having a core structure formed by a plurality of monosaccharide residues of a plurality of kinds, and mass information corresponding to each of the plurality of kinds of glycans, based on the glycan composition set through the glycan composition setting section;
• a mass-changing factor setting section configured to allow a setting of mass-changing factors causing a mass change of a glycan;
• and
• a theoretical glycan mass calculation section configured to determine a theoretical glycan mass-to-charge ratio after the mass change of the glycan occurs, of each of the plurality of kinds of glycans acquired by the glycan information acquisition section, based on the mass-changing factors set through the mass-changing factor setting section,
• where:
• the mass-changing factor setting section sets, as the mass-changing factors, an ion species or salt that is possibly formed on a carboxyl group of a sialic acid in a sialic-acid-linked glycan included in the analysis target, and a sialic-acid linkage type in which a mass change corresponding to the derivatization treatment possibly occurs;
• and
• the theoretical glycan mass calculation section includes a mass change calculation section configured to determine an amount of mass change estimated from a combination of the ion species or the salt and the sialic-acid linkage type.