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US 2022/0187586 A1Published application
Systems and methods for sample positioning to facilitate microscopy
AssigneeThe Administrators of the Tulane Educational Fund
InventorsJonathon Quincy BROWN, Samuel Jacob LEUTHY, Max Sebastian COOPER
Life of this patent
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Abstract
In order to remove the need for manual re-positioning of a sample (e.g., a tissue sample) on a microscope stage, systems and methods for sample positioning are described. A sample can be attached to a tissue positioning device. Then a microscope can be used to take a plurality of microscopy images (e.g., 2-dimensional, 3-dimensional, etc.) of a surface of the sample in a rotational geometry using the tissue positioning device to facilitate the microscopy.
Claims20
A system comprising:
- a tissue positioning device comprising:
- a tissue holding mechanism configured to hold at least a portion of a tissue sample;
- and
- a motorized mechanism, comprising at least one motor, configured to raise, lower, and rotate the tissue holding mechanism,
- wherein the tissue holding mechanism comprises at least two portions configured to be secured in joints of the motorized mechanism;
- and
- a microscope configured to image a surface of the tissue sample in a plurality of configurations to provide a visualization of at least a portion of the tissue sample.
4 more elements
A method comprising:
- attaching a tissue sample to a tissue positioning device;
- and
- using a microscope to take a plurality of microscopy images of a surface of the tissue sample in a rotational geometry using the tissue positioning device.
Dependencies are inferred from the claim text.