Immunoassay reagent and immunoassay method
AssigneeSekisui Medical Co., Ltd.
InventorsMieko OTA, Yuuya INABA, Hiroki KOBAYASHI, Mitsuaki YAMAMOTO
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Abstract
The problem to be solved by the present invention is to provide a reagent that can reduce deposition of fouling in the reaction cell, by using an existing reaction cell, without affecting the composition of the reagent, in an immunoassay method using a reagent containing latex particles; and to provide an immunoassay method using the reagent. Provided is an immunoassay reagent including a latex particle, wherein the latex particle contains a halogen atom. Also provided is an immunoassay method including contacting a latex particle with a sample to be measured in a reaction cell, wherein the latex particle contains a halogen atom.
Claims13
1-16. (canceled)
An immunoassay reagent comprising polystyrene latex particles, wherein the polystyrene latex particles each comprise fluorine.
A reagent for measuring HbA1c comprising at least:
- polystyrene latex particles each comprising fluorine;
- and an antibody against HbA1c.
A latex immunoassay reagent for measuring HbA1c, comprising:
- (1) a first reagent comprising polystyrene latex particles each comprising fluorine;
- and
- (2) a second reagent comprising an anti-HbA1c monoclonal antibody.
An immunoassay method, comprising:
- contacting polystyrene latex particles with a sample to be measured in a reaction cell,
- wherein the polystyrene latex particles each contain fluorine.
A method for measuring HbA1c, comprising:
- contacting polystyrene latex particles each comprising fluorine with an antibody against HbA1c and a sample in a reaction cell.
A method for measuring HbA1c, comprising:
- (1) contacting polystyrene latex particles each containing fluorine with a sample in a reaction cell to adsorb HbA1c contained in the sample to the latex particles;
- and
- (2) contacting the HbA1c adsorbed to the polystyrene latex particles contact with an anti-HbA1c monoclonal antibody to agglutinate the polystyrene latex particles.
A method for suppressing fouling in a reaction cell in an immunoassay method, comprising a step of contacting polystyrene latex particles with a sample in the reaction cell, wherein the polystyrene latex particles each comprise fluorine.
A polystyrene latex particle used for immunoassay, wherein the particle comprises fluorine.
Dependencies are inferred from the claim text.