Peak Integration Correction without Parameter Adjustment

A method for selecting an integration area for a chromatographic peak, comprising:

• instructing a separation device to separate a compound from a sample over a time period using a processor;
• instructing a mass spectrometer to measure a plurality of intensities of at least one ion of the separated compound over the time period using the processor, producing a chromatogram;
• and
• identifying at least one peak of the at least one ion from the chromatogram using a peak-finding algorithm and calculating two or more different peak integration areas for the at least one peak by applying the peak-finding algorithm with two or more different values for at least one peak-finding parameter without manual and iterative adjustment of the two or more different values by a user using the processor.

A computer program product, comprising a non-transitory and tangible computer-readable storage medium whose contents include a program with instructions being executed on a processor to perform a method for selecting an integration area for a chromatographic peak, the method comprising:

• providing a system, wherein the system comprises one or more distinct software modules, and wherein the distinct software modules comprise a control module and an analysis module;
• instructing a separation device to separate a compound from a sample over a time period using the control module;
• instructing a mass spectrometer to measure a plurality of intensities of at least one ion of the separated compound over the time period using the control module, producing a chromatogram;
• and
• identifying at least one peak of the at least one ion from the chromatogram using a peak-finding algorithm and calculating two or more different peak integration areas for the at least one peak by applying the peak-finding algorithm with two or more different values for at least one peak-finding parameter without manual and iterative adjustment of the two or more different values by a user using the analysis module.
• displaying on a display device at the same time two or more plots of the at least one peak that each shows a different peak integration area of the two or more different peak integration areas graphically using the display module;
• and
• receiving data from a user selection device that indicates user selection of one of the two or more plots using the user selection module.