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US 2022/0186312 A1Published application
Predictive method for assessing the success of embryo implantation
AssigneeGuzip Biomarkers Corporation
InventorsHung-Cheng Lai, Rui-Lan Huang, Shu-Chuan Lin
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Abstract
A method for identifying a potential biomarker for determining the probability of the success of embryo implantation by assaying a methylation profile of cervical secretions.
Claims8
A method for identifying a potential biomarker for determining the probability of the success of embryo implantation, comprising:
- (1) providing a cervical sample from a female subject;
- (2) assaying nucleic acids of the cervical sample to generate a methylation profile comprising 1733 genes listed in Table 4;
- (3) calculating a statistical value of at least one gene from the 1733 genes in the methylation profile;
- and
- (4) identifying the at least one gene as a biomarker in the cervical sample for determining the probability of the success of embryo implantation when the statistical value of the at least one gene is higher than a threshold value.
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