Use of Haploid Embryonic Cells to Generate Offspring with Predetermined Genomes
OwnerLawrence Charles Smith, Remi Labrecque +3inventors
InventorsLawrence Charles Smith, Remi Labrecque, Luis Miguel Aquila Paredes, Jacinthe Therrien, Christian Vigneault
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Abstract
A method of generating offspring with a precharacterized genome is disclosed. In one embodiment, the method comprises the steps of (a) obtaining ungulate haploid embryonic cells, (b) deriving haploid embryonic outgrowth from the cells of step (a), (c) characterizing the genome of the haploid cells of step (b), and (d) deriving diploid embryos or offspring from the cells of step (c).
Claims22
A method of generating mammalian diploid embryos and/or offspring with a pre-characterized genome comprising the steps of:
- a) obtaining an embryonic haploid cell,
- b) deriving haploid outgrowth from the cell of step (a),
- c) characterizing the genome of the haploid cells of step (a) or (b), and
- d) deriving diploid embryos and/or offspring from the cells of steps (a), (b) or (c).
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Dependencies are inferred from the claim text.