Novel aortic aneurysm marker
AssigneesEiken Kagaku Kabushiki Kaisha, National Cerebral and Cardiovascular Center
InventorsNaoto MINAMINO, Hiroaki YAGI, Mitsuhiro NISHIGORI, Hatsue UEDA, Hitoshi MATSUDA, Yusuke MURAKAMI
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Abstract
The present invention is intended to provide a novel biomarker capable of detecting aortic aneurysm with high sensitivity, and specifically, the present invention relates to a detection marker of aortic aneurysm, comprising an NPC2 (Niemann-Pick disease type C2) protein and/or an IGFBP7 (Insulin-like growth factor-binding protein 7) protein.
Claims19
A method for detecting aortic aneurysm, comprising a step of measuring the following 1) and/or 2) in a sample obtained from a subject:
- 1) an NPC2 (Niemann-Pick disease type C2) protein, and/or
- 2) an IGFBP7 (Insulin-like growth factor-binding protein 7) protein.
A method for detecting or screening a subject having a risk of developing aortic aneurysm in future, comprising a step of measuring the following 1) and/or 2) in a sample obtained from the subject:
- 1) an NPC2 (Niemann-Pick disease type C2) protein, and/or
- 2) an IGFBP7 (Insulin-like growth factor-binding protein 7) protein.
A detection marker of aortic aneurysm, comprising the following 1) and/or 2):
- 1) an NPC2 protein, and/or
- 2) an IGFBP7 protein.
Dependencies are inferred from the claim text.