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US 2022/0178937 A1Published application
QUANTITATIVE DETERMINATION METHOD FOR Hex4, LYSO-GM1, Fuc-GlcNAc-Asn, AND LYSO-SULFATIDE INCLUDED IN CEREBROSPINAL FLUID
AssigneeJCR Pharmaceuticals Co., Ltd.
InventorsHidehiko HASHIMOTO, Satowa TANAKA, Tomoki FUKATSU, Noboru TANAKA
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Abstract
A method for quantifying Hex4, lyso-GM1, Fuc-GlcNAc-Asn, or lyso-sulfatide included in cerebrospinal fluid, the method including adding an internal standard substance to a solution including the cerebrospinal fluid, submitting the solution including the cerebrospinal fluid, to which the internal standard substance has been added, to liquid chromatography to obtain an eluate, and subjecting the eluate to mass analysis.
Claims29
A method for quantifying a substance in cerebrospinal fluid, comprising:
- adding an internal standard substance to a solution including the cerebrospinal fluid;
- applying the solution containing the cerebrospinal fluid, to which the internal standard substance has been added, to liquid chromatography to obtain an eluate;
- and
- subjecting the eluate to mass analysis to quantify the substance.
1 more element
Dependencies are inferred from the claim text.