A sensitive lc-ms assay to measure curcuminoids in complex biological samples
AssigneesThe Regents of the University of California, California State University Channel Island
InventorsKym Francis FAULL, Alexander Jaeoh YOON, Philip HAMPTON
Life of this patent
Estimating the term…
Abstract
A sensitive method for quantitating curcuminoids in biological and other samples is described wherein curcuminoids in the sample are derivatized to boron difluoride curcuminoid complexes then analyzed by liquid chromatography-mass spectroscopy.
Claims24
A method for quantifying one or more curcuminoids and their metabolites present in a sample, the method comprising the steps of derivatizing the curcuminoids in the sample to a boron difluoride curcuminoid complex, and quantifying the boron difluoride curcuminoid complexes by liquid chromatography-tandem mass spectroscopy, thereby quantifying the one of more curcuminoids present in the sample.
Dependencies are inferred from the claim text.