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AssigneesThe University of Bristol, Cancer Research Technology Limited
InventorsDerek Neil Woolfson, William Michael Dawson, Guto Glyn Rhys, David Arne Scott, Jordan Michael Fletcher, Christopher Robin Wells Wood, James Christopher Norman, Cassie Jemma Clarke
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A method of diagnosing, staging or monitoring cancer, the method comprising the steps of: (a) providing a sensor array comprising at least two sensors, wherein each sensor comprises a protein barrel that comprises five or more alpha helices arranged as an alpha-helical barrel, and a reporter dye, wherein the protein barrel defines a lumen, the reporter dye is bound to the lumen reversibly; and wherein the protein barrel is different in structure in the at least two sensors; (b) contacting the sensor array with a sample obtained from a patient; and then (c) comparing the sensor array to a predetermined standard.
A method of diagnosing, staging or monitoring cancer, the method comprising the steps of:
Use of a sensor array comprising at least two sensors, wherein each sensor comprises a protein barrel that comprises five or more alpha helices arranged as an alpha-helical barrel, and a reporter dye, wherein the protein barrel defines a lumen, the reporter dye is bound to the lumen reversibly;
Dependencies are inferred from the claim text.