Back to results
US 2022/0178810 A1Published application
Hydrogel particles with tunable optical properties
AssigneeSlingshot Biosciences, Inc.
InventorsJeffrey KIM, Oliver LIU, Jeremy AGRESTI, Anh Tuan NGUYEN
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to compositions comprising a hydrogel particle with optical properties substantially similar to the optical properties of a target cell, and methods for their use.
Claims36
(canceled)
A population of hydrogel particles, each hydrogel particle comprising:
- (i) a polymer comprising a polymerized monomer and a bifunctional monomer;
- (ii) DNA encapsulated within the hydrogel particle;
- and
- (iii) a nanoparticle encapsulated within the hydrogel,
- wherein the population hydrogel particles has an optical property that is substantially similar to a corresponding property of a target cell, the optical property provided by the polymerized monomer, bifunctional monomer, or the encapsulated nanoparticle.
2 more elements
A population of hydrogel particles, each hydrogel particle comprising:
- (i) a polymer comprising polymerized acrylamide and bis-acrylamide;
- and
- (ii) DNA encapsulated within the hydrogel particle;
- wherein the population hydrogel particles has an average diameter in the range of from 5 μm to 100 μm, and no more than 10% of the hydrogel particles have a diameter exceeding the average diameter of the hydrogel particles by more than 10%.
1 more element
Dependencies are inferred from the claim text.