A method, an electrochemical sensor and a system for selective detection of infections
AssigneesUniversitat Politecnica De Catalunya, B. Braun Surgical S.A.
InventorsBrenda Guadalupe Molina García, Elaine Aparecida Armelin Diggroc, Pau Turon Dols, Carlos Enrique Alemán Llansó
Life of this patent
Estimating the term…
Abstract
A method, an electrochemical sensor and a system for selective detection of infections. The method detects a concentration of nicotinamide adenine dinucleotide, NADH, from a bacterial culture through a cyclic voltammetry or chronoamperometry applied to an electrochemically active polymer. Therefore, prokaryotic cells can be detected while eukaryotic cells remain undetected. The infections can include bacterial infections and fungi or yeasts microbial infections.
Claims15
A method for selective detection of infections, the method comprising detecting a concentration of nicotinamide adenine dinucleotide, NADH, from a bacterial culture through a cyclic voltammetry or chronoamperometry applied to an electrochemically active polymer, wherein the infections include bacterial and/or fungi or yeasts microbial infections.
An electrochemical sensor for selective detection of infections, wherein the infections include bacterial and/or fungi or yeasts microbial infections, the electrochemical sensor comprising:
- a solid substrate acting as a support;
- and
- an electrochemically active polymer deposited on top of said support and configured to be electrochemically activated,
- wherein, when in use, the electrochemical sensor is adapted to be placed over a surface of a device, a part of the surface of the device, or in a body of the device,
- wherein the device is located in a bacterial culture or implanted in a living tissue, and as a result of a cyclic voltammetry or chronoamperometry applied to the electrochemically active polymer, the electrochemically active polymer is configured to detect a concentration of nicotinamide adenine dinucleotide, NADH.
A system for selective detection of infections, wherein the infections include bacterial and/or fungi or yeasts microbial infections, the system comprising:
- a medical device;
- an electrochemical sensor including a solid substrate acting as a support, and an electrochemically active polymer deposited on top of said support and configured to be electrochemically activated, said electrochemical sensor, when in use, being adapted to be placed over the surface, part of the surface or in the body of said medical device;
- and
- means adapted and configured to apply said electrical potential to the electrochemically active polymer,
- wherein the medical device is located in a bacterial culture or located in a living tissue, and as a result of a cyclic voltammetry or chronoamperometry applied to the electrochemically active polymer, the latter is configured to detect a concentration of nicotinamide adenine dinucleotide, NADH.
Dependencies are inferred from the claim text.