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US 2022/0177928 A1Published application
Production of squalene from hyper-producing yeasts
AssigneeNovartis AG
InventorMichael BROEKER
Life of this patent
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Abstract
A method for preparing purified yeast is disclosed, where the squalene source is a yeast that hyperproduces squalene. The squalene is useful for pharmaceutical purposes. For instance, it can be used to prepare an oil-in-water emulsion, and the emulsion is particularly suitable for use as an immmological adjuvant.
Claims21
1-22. (canceled).
A process for preparing purified squalene for parenteral use in humans, comprising the steps of:
- (a) growing a yeast culture under conditions such that the yeast comprises at least 2% cell dry weight squalene;
- (b) purifying squalene from the cultured yeast, such that the squalene is of pharmaceutical grade
Dependencies are inferred from the claim text.