Compositions and methods to treat viral infection and co-morbidities
AssigneesThe Regents of the University of California, The George Washington University, Baker Heart and Diabetes Research Institute.
InventorsYury MILLER, Michael BUKRINSKY, Dmitri SVIRIDOV
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Abstract
In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for preventing or slowing the spread of a viral infection, wherein optionally the viral infection is a coronavirus infection, optionally a COVID-19 infection or variant thereof, or a human immunodeficiency virus (HIV) infection, preventing or decreasing coronavirus or HIV-co-morbidities in an individual, or inhibiting, or slowing the rate of, coronavirus (optionally COVID-19) or HIV replication in vitro and in vitro.
Claims9
A method for:
- preventing or slowing the spread of a viral infection, wherein optionally the viral infection is a coronavirus infection, optionally a COVID-19 infection, or a human immunodeficiency virus (HIV) infection,
- preventing or decreasing coronavirus (optionally COVID-19) or HIV-co-morbidities in an individual,
- preventing or decreasing sequelae diseases, conditions or symptoms of coronavirus (optionally COVID-19) or HIV, or preventing or decreasing the severity of long COVID syndrome, or
- inhibiting, or slowing the rate of, coronavirus (optionally COVID-19) or HIV replication in vitro and in vitro,
- the method comprising:
- (a)
- (i) providing or having provided a protein or a composition having Apolipoprotein A-I binding protein (AIBP) activity, and
- (ii) administering to an individual in need thereof the protein or the composition having Apolipoprotein A-I binding protein (AIBP) activity;
- or
- (b) administering to an individual in need thereof a protein or a composition having Apolipoprotein A-I binding protein (AIBP) activity.
Dependencies are inferred from the claim text.