Pyrazolopyrimidine compound, pharmaceutical composition, and application therefor
AssigneeCentral China Normal University
InventorsGuangfu Yang, Wei Huang, Linsheng Zhuo, Hongchuang Xu, Mingshu Wang
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AssigneeCentral China Normal University
InventorsGuangfu Yang, Wei Huang, Linsheng Zhuo, Hongchuang Xu, Mingshu Wang
Estimating the term…
The present invention relates to the field of biomedicine, and discloses a pyrazolopyrimidine compound, a pharmaceutical composition, and an application therefor, the oxygen-containing substituted pyrazolopyrimidine compound having the structure shown in formula (I). The oxygen-containing substituted pyrazolopyrimidine compound having the structure shown in formula (I) provided in the present invention or a pharmaceutically acceptable salt, a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvate, a metabolite, or a prodrug thereof demonstrate excellent inhibitory activity against TRK kinase, and demonstrate good anti-tumour activity at the animal level.
A pyrazolopyrimidine compound having a structure represented by formula (I), or a pharmaceutically acceptable salt thereof, or a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvate, a metabolite, or a prodrug thereof,
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Dependencies are inferred from the claim text.