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US 2022/0177453 A1Published application
Crystallization of smac mimic used as iap inhibitor and preparation method thereof
AssigneeChia Tai Tianqing Pharmaceutical Group Co., Ltd.
InventorsYingchun Liu, Zhaobing Xu, Lihong Hu, Charles Z. Ding, Xingxun Zhu, Shuhui Chen
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Abstract
Provided are a crystallization of an SMAC mimic used as an IAP inhibitor and a preparation method thereof; also comprised is the use of said crystallization in the preparation of a drug for treating cancer benefiting from cIAP1 inhibition. The compound of formula (I) has high crystallization stability and low hygroscopicity, and has advantages in terms of physical properties, safety, and metabolic stability, and has high drug value.
Claims19
A crystalline form of a compound of formula (I)
Dependencies are inferred from the claim text.