Preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile

A preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile, comprising the following steps:

• step 1:
• in the presence of Li2CuCl4, adding a solution of p-nitrochlorobenzene-zinc in a second solvent dropwise to a solution of 1-chlorocyclopentanecarbonitrile in a first solvent to prepare a compound 1-(4-nitrophenyl)cyclopentanecarbonitrile;
• and
• step 2:
• subjecting the compound 1-(4-nitrophenyl)cyclopentanecarbonitrile obtained in step 1 to a nitroreduction reaction in a third solvent under the action of a catalyst to prepare the compound 1-(4-aminophenyl)cyclopentanecarbonitrile;
• wherein a reaction equation is as follows:
• the first solvent used in step 1 is one from the group consisting of toluene, xylene, benzene, diethyl ether, chloroform, and tetrahydrofuran (THF);
• the second solvent used in step 1 is one from the group consisting of toluene, diethyl ether, THF, and dimethyl sulfoxide (DMSO);
• and
• the third solvent used in step 2 is one from the group consisting of ethanol, methanol, and isobutanol.