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US 2022/0177414 A1Published application
Method for preparing an n-cyclopropylmethyl aniline compound
AssigneeJiangxi Univate New Material Co., Ltd.
InventorsChaoqun HUANG, Jintao ZHU, Liang LV, Liangming LUO, Rong ZHANG, Jiyong LIU
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Abstract
Provided is a method for preparing an N-cyclopropylmethyl aniline compound, which comprises hydrogenating a compound represented by Formula II and cyclopropyl formaldehyde as raw materials in the presence of an acid and catalyst to generate an N-cyclopropylmethyl aniline compound represented by Formula I, wherein R is alkoxy, alkylamino or a substituted anilino group represented by Formula III.
Claims30
A method for preparing an N-cyclopropylmethyl aniline compound, comprising:
- hydrogenating a compound represented by Formula II and cyclopropyl formaldehyde as raw materials in the presence of an acid and a catalyst to generate an N-cyclopropylmethyl aniline compound represented by Formula I according to the scheme as follows:
- wherein R is selected from alkoxy, alkylamino or a substituted anilino group represented by Formula III:
- wherein R1 is selected from methoxy or fluorine, R2 is selected from fluorine or trifluoromethyl, R3 is selected from any one of H, fluorine, chlorine, bromine, iodine, nitro or trifluoromethyl, and R4 is selected from any one of trifluoromethyl, trifluoromethoxy or difluoromethoxy;
- and represents the position at which the group is attached.
1 more element
Dependencies are inferred from the claim text.