Treating myelomas
AssigneeMayo Foundation for Medical Education and Research
InventorsSvetomir N. Markovic, Wendy K. Nevala
Life of this patent
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Abstract
This document provides methods and materials related to treating myelomas. For example, methods and materials re-lating to the use of a composition containing albumin-containing nanoparticle/antibody complexes (e.g., ABRAXANE®/anti-CD38 polypeptide antibody complexes) to treat myelomas are provided.
Claims25
A method for treating a mammal having myeloma, said method comprising administering to said mammal a composition comprising nanoparticles containing albumin and paclitaxel complexed with an anti-CD38 polypeptide antibody, wherein an average diameter of the nanoparticles is less than 1 μm.
2-3. (canceled)
12-15. (canceled)
17-25. (canceled)
27-33. (canceled)
The method of claim 17, wherein said administration of said composition increases a median time to progression for a population of mammals with said myeloma is at least 170 days.
43-72. (canceled)
Dependencies are inferred from the claim text.