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US 2022/0175945 A1Published application
Antibodies and enonomers
AssigneeEnosi Therapeutics Corporation
InventorH. Michael SHEPARD
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Abstract
The subject invention provides a composition comprising an enomomer which comprises a) a carrier molecule, and b) at least one aptamer, wherein the carrier molecule is an antibody, an antigen-binding moiety, a serum protein, an intracellular protein, a messenger RNA (mRNA) or human serum albumin.
Claims72
A composition, comprising an enonomer, wherein:
- the enonomer comprises a) a carrier molecule, and b) at least one aptamer;
- the carrier molecule is an antibody, an antigen-binding moiety, a serum protein, an intracellular protein, a messenger RNA (mRNA), or human serum albumin;
- the antibody or antigen-binding moiety does not bind the same target molecule or target receptor as the aptamer, whereby the enonomer has bi-specific activity;
- and
- the half-life of the enonomer is equal to or greater than 10 hours.
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Dependencies are inferred from the claim text.