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US 2022/0175932 A1Published application
Polymer system for ophthalmic drug delivery
AssigneeMcMaster University
InventorsHeather SHEARDOWN, Mitchell ROSS, Talena RAMBARRAN
Life of this patent
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Abstract
This application relates to a thermo-gel polymer system useful for ophthalmic drug delivery. The thermo-gel comprises a polymer and chitosan, and the polymer comprises monomers of N-isopropylacrylamide (NIPAAm), acrylic acid (AA) and at least one hydrophobic monomer.
Claims22
A thermo-gel comprising:
- a) a polymer (pNAX), comprised of monomers of N (N-isopropylacrylamide (NIPAAm)), A (acrylic acid (AA)) and X (a hydrophobic monomer);
- and
- b) chitosan,
- wherein the chitosan is covalently or ionically bonded to the polymer.
1 more element
The present application also includes a method of improving mucoadhesive properties of a thermo-gel comprising incorporating one or more monomers comprising a disulfide moiety into a polymer comprised in the thermo-gel.
Dependencies are inferred from the claim text.