Methods and compositions comprising a c-terminal bax peptide
AssigneeUniversity of Central Florida Research Foundation, Inc.
InventorsAnnette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
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Abstract
In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
Claims14
-10. (canceled)
A method for treating a microbial infection in a subject, comprising administering to the subject an effective amount of a composition comprising a C-terminal B cell lymphoma-2 (Bcl-2)-associated X protein (Bax) peptide (CT20p peptide), wherein the CT20p peptide comprises the amino acid sequence of SEQ ID NO:
- 1, 2, 3, or 4.
Dependencies are inferred from the claim text.