Lactobacillus paracasei strain and use thereof
AssigneeKobiolabs, Inc.
InventorsGwang Pyo Ko, Woonki Kim, You-Jin Jang, Boram Seo, June-Chul Lee, Tae-Wook Nam, Insu Kim, Jin-Woo Lee
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AssigneeKobiolabs, Inc.
InventorsGwang Pyo Ko, Woonki Kim, You-Jin Jang, Boram Seo, June-Chul Lee, Tae-Wook Nam, Insu Kim, Jin-Woo Lee
Estimating the term…
Human-derived probiotic strains Lactobacillus paracasei KBL382, Lactobacillus paracasei KBL384 and Lactobacillus paracasei KBL385 are described, as well as uses of the strains for improving intestinal health and treating or preventing intestinal diseases. The strains have excellent anti-inflammatory and immunomodulatory functions, superb strengthening effects on tight junctions of the intestinal tract wall, suppress enteritis-induced weight loss and colon length reduction, thereby exhibiting therapeutic effects for enteritis, and significantly alleviate the symptoms of atopic dermatitis. The strains can be used as probiotic material for enhancing anti-inflammatory effects, strengthening immunity, improving intestinal health functions, and alleviating allergic diseases.
A composition in a form of capsule, tablet, emulsion or powder, comprising:
A method for treating, alleviating or preventing intestinal disease, allergic disease, autoimmune disease or inflammatory disease, comprising administering a therapeutically effective amount of at least one selected from a strain of Lactobacillus paracasei selected from Lactobacillus paracasei KBL384 with Accession No. KCTC13510BP, Lactobacillus paracasei KBL385 with Accession No. KCTC13511BP, cultures of said strain, lysates of said strains, and extracts of said strains.
A composition, comprising:
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